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S-PRG filler¸¦ Æ÷ÇÔÇÑ Ä¡¸é¿­±¸Àü»öÁ¦ÀÇ Streptococcus mutans¿¡ ´ëÇÑ Ç׹̻ý¹° Ư¼º¿¡ °üÇÑ ¿¬±¸

Antibacterial Properties of Pit and Fissure Sealant Containing S-PRG filler on Streptococcus mutans

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¾ÈÁø¼±:An Jin-Seon ¹ÚÈ£¿ø:Park Ho-Won/¼­Çö¿ì:Seo Hyun-Woo/À̽ÿµ:Lee Si-Young

Abstract

º» ¿¬±¸´Â Planktonic growth inhibition test¿Í CDC Biofilm Reactor¸¦ »ç¿ëÇÑ Biofilm assay¸¦ ÅëÇØ S-PRG filler¸¦ ÇÔÀ¯ÇÏ´Â Ä¡¸é¿­±¸Àü»öÁ¦ÀÇ S. mutans¿¡ ´ëÇÑ Ç׹̻ý¹° È¿°ú¸¦ ±âÁ¸ÀÇ Ä¡¸é¿­±¸Àü»öÁ¦¿Í ºñ±³ÇÏ°íÀÚ ÇÏ¿´´Ù.
S-PRG ÇÊ·¯¸¦ ÇÔÀ¯ÇÏ´Â Ä¡¸é¿­±¸Àü»öÁ¦ÀÎ BeautiSealant, ºÒ¼Ò¸¦ ¹æÃâÇÏ´Â Ä¡¸é¿­±¸Àü»öÁ¦ÀÎ Clinpro¢â sealant, ºÒ¼Ò ¹Ì¹æÃâ Ä¡¸é¿­±¸Àü»öÁ¦ÀÎ Concise¢â sealant¸¦ ½ÇÇ豺À¸·Î ¼±Á¤ÇÏ¿´´Ù.
¼ºÀå¾ïÁ¦Æò°¡¸¦ À§ÇØ Ä¡¸é¿­±¸Àü»öÁ¦¸¦ »ç¿ëÇÏÁö ¾ÊÀº ±ºÀ» À½¼º ´ëÁ¶±ºÀ¸·Î ¼³Á¤ÇÏ¿´À¸¸ç, 3°³ÀÇ ½ÇÇ豺 ¸ðµÎ ´ëÁ¶±ºº¸´Ù À¯ÀÇÇÒ Á¤µµ·Î ³·Àº Áý¶ô Çü¼º ´ÜÀ§¸¦ º¸¿´°í, Clinpro¢â sealant°¡ BeautiSealant¿Í Concise¢â sealantº¸´Ù À¯ÀÇÇÒ Á¤µµ·Î ³·Àº Áý¶ô Çü¼º ´ÜÀ§¸¦ º¸¿´´Ù. BeautiSealant¿Í Concise¢â sealant ±º°£¿¡´Â À¯ÀÇÇÑ Â÷ÀÌ°¡ °üÂûµÇÁö ¾Ê¾Ò´Ù.
¹ÙÀÌ¿À Çʸ§ Æò°¡¿¡¼­µµ Clinpro¢â sealant±ºÀÌ BeautiSealant¿Í Concise¢â sealant±ºµé¿¡ ºñÇØ À¯ÀÇÇÒ Á¤µµ·Î ³·Àº Áý¶ô Çü¼ºÀ» º¸¿´À¸¸ç, BeautiSealant¿Í Concise¢â sealant ±º°£¿¡ À¯ÀÇÇÑ Â÷ÀÌ´Â °üÂûµÇÁö ¾Ê¾Ò´Ù.
º» ¿¬±¸ °á°ú S-PRG filler¸¦ Æ÷ÇÔÇÏ´Â Ä¡¸é¿­±¸Àü»öÁ¦ÀÎ BeautiSealant´Â ±âÁ¸ÀÇ ºÒ¼Ò¹æÃâ Ä¡¸é¿­±¸Àü»öÁ¦¿¡ ºñÇÏ¿© ³·Àº Ç׹̻ý¹° È¿°ú¿Í ³ôÀº ¹ÙÀÌ¿À Çʸ§ Çü¼º´ÉÀ» º¸¿´´Ù.

The purpose of this study was to evaluate the antibacterial properties of a sealant containing S-PRG filler compared to those of two contemporary commercial sealants to determine the inhibition of bacterial growth in broth culture and biofilm formation using the CDC Biofilm Reactor. The BeautiSealant containing S-PRG filler, the fluoride releasing Clinpro¢â sealant, which are known to have higher antibacterial effects, and the non-fluoride releasing Concise¢â sealant were selected for this study. A Streptococcus mutans culture in BHI broth without sealant served as a negative control in the planktonic growth inhibition test. As a result, bacterial growth was inhibited in all three sealant groups compared to that in the control. The Clinpro¢â sealant showed a significantly reduced number of CFUs compared to those of the BeautiSealant and Concise¢â sealants. However, no significant difference was detected between the BeautiSealant and Concise¢â sealants. The Clinpro¢â sealant significantly decreased biofilm formation compared to that by the BeautiSealant and Concise¢â sealants. No significant difference was observed between the BeautiSealant and Concise¢â sealants. In conclusion, the sealant containing S-PRG filler had a less potent anti-bacterial property and increased biofilm formation capacity compared to those of the fluoride releasing Clinpro¢â sealant.

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S-PRG filler; BeautiSealant; Pit and fissure sealants; Streptococcus mutans; Fluoride

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